Progesterone vs Estrogen

By Dr Kelly

June 27, 2023

The Balance of Estrogen and Progesterone

Progesterone and estrogen balance each other through a delicate interplay in the female body. Estrogen, primarily produced by the ovaries, promotes the growth and development of the uterus and other reproductive organs, stimulates the thickening of the uterine lining, and plays a role in secondary sexual characteristics. However, excessive estrogen levels without sufficient progesterone can lead to hormonal imbalance and potential health issues.


Progesterone, produced mainly by the ovaries and the placenta during pregnancy, acts as a counterbalance to estrogen. It helps prepare the uterus for pregnancy, maintains the uterine lining, and supports embryo implantation. Progesterone also has calming and anti-inflammatory effects on the body, promotes bone health, and contributes to the regulation of menstrual cycles.


During the menstrual cycle, estrogen levels rise in the first half, stimulating the growth of the uterine lining. In the second half, progesterone levels increase in response to ovulation, helping to stabilize and thicken the uterine lining for potential implantation of a fertilized egg. If pregnancy does not occur, progesterone levels decrease, leading to the shedding of the uterine lining during menstruation.

Balance between Progesterone and Estrogen

This delicate balance between estrogen and progesterone is crucial for reproductive health and overall hormonal equilibrium in women. When there is an imbalance, such as estrogen dominance or insufficient progesterone, it can lead to various symptoms and conditions, including irregular menstrual cycles, PMS, infertility, mood swings, and hormonal disorders.

Achieving hormonal balance often involves lifestyle changes, stress management, a healthy diet, and, in some cases, medical interventions. Hormone replacement therapy may be prescribed to restore balance in certain situations, such as menopause. It's important to consult with a healthcare professional to assess individual hormone levels, determine the underlying cause of imbalance, and develop an appropriate treatment plan tailored to specific needs.

About the author

Dr. Kelly has 25 years of expert medical experience caring for the sickest of the sick people in critical care (including ICU, Heart surgery, Heart & Lung transplant surgery, as well as cardiology). She is a clinical specialist who has taken care of and trained others to care for the critically ill/the elderly and developed many screening and preventative programs to help improve the health of the population. The reality is that most people just don't have to be that sick. or stay that sick. So, Dr. Kelly decided to change the focus of the care she provided: to prevent, reverse and restore the health of individuals.

Dr. Kelly

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